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Of Keeping and Tipping the Balance: Host Regulation and Viral Modulation of IRF3-Dependent IFNB1 Expression

The type I interferon (IFN) response is a principal component of our immune system that allows to counter a viral attack immediately upon viral entry into host cells. Upon engagement of aberrantly localised nucleic acids, germline-encoded pattern recognition receptors convey their find via a signall...

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Detalles Bibliográficos
Autores principales: Schwanke, Hella, Stempel, Markus, Brinkmann, Melanie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411613/
https://www.ncbi.nlm.nih.gov/pubmed/32645843
http://dx.doi.org/10.3390/v12070733