Multi-Laboratory Comparison of Next-Generation to Sanger-Based Sequencing for HIV-1 Drug Resistance Genotyping

Next-generation sequencing (NGS) is increasingly used for HIV-1 drug resistance genotyping. NGS methods have the potential for a more sensitive detection of low-abundance variants (LAV) compared to standard Sanger sequencing (SS) methods. A standardized threshold for reporting LAV that generates dat...

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Detalles Bibliográficos
Autores principales: Parkin, Neil T., Avila-Rios, Santiago, Bibby, David F., Brumme, Chanson J., Eshleman, Susan H., Harrigan, P. Richard, Howison, Mark, Hunt, Gillian, Ji, Hezhao, Kantor, Rami, Ledwaba, Johanna, Lee, Emma R., Matías-Florentino, Margarita, Mbisa, Jean L., Noguera-Julian, Marc, Paredes, Roger, Rivera-Amill, Vanessa, Swanstrom, Ronald, Zaccaro, Daniel J., Zhang, Yinfeng, Zhou, Shuntai, Jennings, Cheryl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411816/
https://www.ncbi.nlm.nih.gov/pubmed/32605062
http://dx.doi.org/10.3390/v12070694

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