Cargando…
The GABA(B) Receptor—Structure, Ligand Binding and Drug Development
The γ-aminobutyric acid (GABA) type B receptor (GABA(B)-R) belongs to class C of the G-protein coupled receptors (GPCRs). Together with the GABA(A) receptor, the receptor mediates the neurotransmission of GABA, the main inhibitory neurotransmitter in the central nervous system (CNS). In recent decad...
Autores principales: | Evenseth, Linn Samira Mari, Gabrielsen, Mari, Sylte, Ingebrigt |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411975/ https://www.ncbi.nlm.nih.gov/pubmed/32646032 http://dx.doi.org/10.3390/molecules25133093 |
Ejemplares similares
-
In Silico Methods for the Discovery of Orthosteric GABA(B) Receptor Compounds
por: Evenseth, Linn M., et al.
Publicado: (2019) -
Exploring Conformational Dynamics of the Extracellular Venus flytrap Domain of the GABA(B) Receptor:
A Path-Metadynamics Study
por: Evenseth, Linn S. M., et al.
Publicado: (2020) -
Ligand-guided homology modelling of the GABA(B2) subunit of the GABA(B) receptor
por: Freyd, Thibaud, et al.
Publicado: (2017) -
A short update on the structure of drug binding sites on neurotransmitter transporters
por: Gabrielsen, Mari, et al.
Publicado: (2011) -
Homology Modeling of Human γ-Butyric Acid Transporters and the Binding of Pro-Drugs 5-Aminolevulinic Acid and Methyl Aminolevulinic Acid Used in Photodynamic Therapy
por: Baglo, Yan, et al.
Publicado: (2013)