Pseudomonas Phage PaBG—A Jumbo Member of an Old Parasite Family

Bacteriophage PaBG is a jumbo Myoviridae phage isolated from water of Lake Baikal. This phage has limited diffusion ability and thermal stability and infects a narrow range of Pseudomonas aeruginosa strains. Therefore, it is hardly suitable for phage therapy applications. However, the analysis of th...

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Autores principales: Evseev, Peter, Sykilinda, Nina, Gorshkova, Anna, Kurochkina, Lidia, Ziganshin, Rustam, Drucker, Valentin, Miroshnikov, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412058/
https://www.ncbi.nlm.nih.gov/pubmed/32635178
http://dx.doi.org/10.3390/v12070721
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author Evseev, Peter
Sykilinda, Nina
Gorshkova, Anna
Kurochkina, Lidia
Ziganshin, Rustam
Drucker, Valentin
Miroshnikov, Konstantin
author_facet Evseev, Peter
Sykilinda, Nina
Gorshkova, Anna
Kurochkina, Lidia
Ziganshin, Rustam
Drucker, Valentin
Miroshnikov, Konstantin
author_sort Evseev, Peter
collection PubMed
description Bacteriophage PaBG is a jumbo Myoviridae phage isolated from water of Lake Baikal. This phage has limited diffusion ability and thermal stability and infects a narrow range of Pseudomonas aeruginosa strains. Therefore, it is hardly suitable for phage therapy applications. However, the analysis of the genome of PaBG presents a number of insights into the evolutionary history of this phage and jumbo phages in general. We suggest that PaBG represents an ancient group distantly related to all known classified families of phages.
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spelling pubmed-74120582020-08-25 Pseudomonas Phage PaBG—A Jumbo Member of an Old Parasite Family Evseev, Peter Sykilinda, Nina Gorshkova, Anna Kurochkina, Lidia Ziganshin, Rustam Drucker, Valentin Miroshnikov, Konstantin Viruses Article Bacteriophage PaBG is a jumbo Myoviridae phage isolated from water of Lake Baikal. This phage has limited diffusion ability and thermal stability and infects a narrow range of Pseudomonas aeruginosa strains. Therefore, it is hardly suitable for phage therapy applications. However, the analysis of the genome of PaBG presents a number of insights into the evolutionary history of this phage and jumbo phages in general. We suggest that PaBG represents an ancient group distantly related to all known classified families of phages. MDPI 2020-07-03 /pmc/articles/PMC7412058/ /pubmed/32635178 http://dx.doi.org/10.3390/v12070721 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Evseev, Peter
Sykilinda, Nina
Gorshkova, Anna
Kurochkina, Lidia
Ziganshin, Rustam
Drucker, Valentin
Miroshnikov, Konstantin
Pseudomonas Phage PaBG—A Jumbo Member of an Old Parasite Family
title Pseudomonas Phage PaBG—A Jumbo Member of an Old Parasite Family
title_full Pseudomonas Phage PaBG—A Jumbo Member of an Old Parasite Family
title_fullStr Pseudomonas Phage PaBG—A Jumbo Member of an Old Parasite Family
title_full_unstemmed Pseudomonas Phage PaBG—A Jumbo Member of an Old Parasite Family
title_short Pseudomonas Phage PaBG—A Jumbo Member of an Old Parasite Family
title_sort pseudomonas phage pabg—a jumbo member of an old parasite family
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412058/
https://www.ncbi.nlm.nih.gov/pubmed/32635178
http://dx.doi.org/10.3390/v12070721
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