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Marine Excitatory Amino Acids: Structure, Properties, Biosynthesis and Recent Approaches to Their Syntheses

This review considers the results of recent studies on marine excitatory amino acids, including kainic acid, domoic acid, dysiherbaine, and neodysiherbaine A, known as potent agonists of one of subtypes of glutamate receptors, the so-called kainate receptors. Novel information, particularly concerni...

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Detalles Bibliográficos
Autores principales: Stonik, Valentin A., Stonik, Inna V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412112/
https://www.ncbi.nlm.nih.gov/pubmed/32635311
http://dx.doi.org/10.3390/molecules25133049
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author Stonik, Valentin A.
Stonik, Inna V.
author_facet Stonik, Valentin A.
Stonik, Inna V.
author_sort Stonik, Valentin A.
collection PubMed
description This review considers the results of recent studies on marine excitatory amino acids, including kainic acid, domoic acid, dysiherbaine, and neodysiherbaine A, known as potent agonists of one of subtypes of glutamate receptors, the so-called kainate receptors. Novel information, particularly concerning biosynthesis, environmental roles, biological action, and syntheses of these marine metabolites, obtained mainly in last 10–15 years, is summarized. The goal of the review was not only to discuss recently obtained data, but also to provide a brief introduction to the field of marine excitatory amino acid research.
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spelling pubmed-74121122020-08-25 Marine Excitatory Amino Acids: Structure, Properties, Biosynthesis and Recent Approaches to Their Syntheses Stonik, Valentin A. Stonik, Inna V. Molecules Review This review considers the results of recent studies on marine excitatory amino acids, including kainic acid, domoic acid, dysiherbaine, and neodysiherbaine A, known as potent agonists of one of subtypes of glutamate receptors, the so-called kainate receptors. Novel information, particularly concerning biosynthesis, environmental roles, biological action, and syntheses of these marine metabolites, obtained mainly in last 10–15 years, is summarized. The goal of the review was not only to discuss recently obtained data, but also to provide a brief introduction to the field of marine excitatory amino acid research. MDPI 2020-07-03 /pmc/articles/PMC7412112/ /pubmed/32635311 http://dx.doi.org/10.3390/molecules25133049 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Stonik, Valentin A.
Stonik, Inna V.
Marine Excitatory Amino Acids: Structure, Properties, Biosynthesis and Recent Approaches to Their Syntheses
title Marine Excitatory Amino Acids: Structure, Properties, Biosynthesis and Recent Approaches to Their Syntheses
title_full Marine Excitatory Amino Acids: Structure, Properties, Biosynthesis and Recent Approaches to Their Syntheses
title_fullStr Marine Excitatory Amino Acids: Structure, Properties, Biosynthesis and Recent Approaches to Their Syntheses
title_full_unstemmed Marine Excitatory Amino Acids: Structure, Properties, Biosynthesis and Recent Approaches to Their Syntheses
title_short Marine Excitatory Amino Acids: Structure, Properties, Biosynthesis and Recent Approaches to Their Syntheses
title_sort marine excitatory amino acids: structure, properties, biosynthesis and recent approaches to their syntheses
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412112/
https://www.ncbi.nlm.nih.gov/pubmed/32635311
http://dx.doi.org/10.3390/molecules25133049
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