Otoprotective Effect of 2,3,4′,5-Tetrahydroxystilbene-2-O-β-d-Glucoside on Gentamicin-Induced Apoptosis in Mouse Cochlear UB/OC-2 Cells

Excessive levels of reactive oxygen species (ROS) lead to mitochondrial damage and apoptotic cell death in gentamicin-induced ototoxicity. 2,3,4’,5-Tetrahydroxystilbene-2-O-β-d-glucoside (THSG), a bioactive constituent, isolated from Polygonum multiflorum Thunb., exhibits numerous biological benefit...

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Detalles Bibliográficos
Autores principales: Wen, Yu-Hsuan, Lin, Jia-Ni, Wu, Rong-Shuan, Yu, Szu-Hui, Hsu, Chuan-Jen, Tseng, Guo-Fang, Wu, Hung-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412181/
https://www.ncbi.nlm.nih.gov/pubmed/32640539
http://dx.doi.org/10.3390/molecules25133070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412181/
https://www.ncbi.nlm.nih.gov/pubmed/32640539
http://dx.doi.org/10.3390/molecules25133070

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