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“DIY” Silica Nanoparticles: Exploring the Scope of a Simplified Synthetic Procedure and Absorbance-Based Diameter Measurements

In this study, the classical Stöber silica synthesis protocol was used to test the limits of simplification in the preparation and size determination of nanoparticles. The scope of three-ingredient, one-pot synthesis was established in conditions of regular 96% and 99.8% ethanol as solvent, with aqu...

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Autores principales: Tabisz, Łukasz, Stanek, Jerzy, Łęska, Bogusława
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412208/
https://www.ncbi.nlm.nih.gov/pubmed/32664284
http://dx.doi.org/10.3390/ma13143088
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author Tabisz, Łukasz
Stanek, Jerzy
Łęska, Bogusława
author_facet Tabisz, Łukasz
Stanek, Jerzy
Łęska, Bogusława
author_sort Tabisz, Łukasz
collection PubMed
description In this study, the classical Stöber silica synthesis protocol was used to test the limits of simplification in the preparation and size determination of nanoparticles. The scope of three-ingredient, one-pot synthesis was established in conditions of regular 96% and 99.8% ethanol as solvent, with aqueous ammonia as the only source of base and water. Particles with diameters in the 15–400 nm range can be reliably obtained with this straightforward approach, and the direct relationship between the size and the product of concentrations of water and ammonia is evidenced. Furthermore, the idea of a linear approximation for Mie scattering in particular conditions is discussed, using experimental data and theoretical calculations. A simple, fast method for particle size determination utilizing a UV-Vis spectrophotometer—an easily accessible instrument—is explained, and shows a level of error (<0.5 SD) that can be acceptable for less rigorous laboratory use of nanoparticles or serve as a quick means for testing the influence of minor alterations to known synthetic protocols. This work aims to show that nanoparticle synthesis can (and should) become a regular occurrence, even in non-specialized labs, facilitating research into their new applications and inspiring outside-the-box solutions, while discussing the drawbacks of a more relaxed synthetic regimen.
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spelling pubmed-74122082020-08-17 “DIY” Silica Nanoparticles: Exploring the Scope of a Simplified Synthetic Procedure and Absorbance-Based Diameter Measurements Tabisz, Łukasz Stanek, Jerzy Łęska, Bogusława Materials (Basel) Article In this study, the classical Stöber silica synthesis protocol was used to test the limits of simplification in the preparation and size determination of nanoparticles. The scope of three-ingredient, one-pot synthesis was established in conditions of regular 96% and 99.8% ethanol as solvent, with aqueous ammonia as the only source of base and water. Particles with diameters in the 15–400 nm range can be reliably obtained with this straightforward approach, and the direct relationship between the size and the product of concentrations of water and ammonia is evidenced. Furthermore, the idea of a linear approximation for Mie scattering in particular conditions is discussed, using experimental data and theoretical calculations. A simple, fast method for particle size determination utilizing a UV-Vis spectrophotometer—an easily accessible instrument—is explained, and shows a level of error (<0.5 SD) that can be acceptable for less rigorous laboratory use of nanoparticles or serve as a quick means for testing the influence of minor alterations to known synthetic protocols. This work aims to show that nanoparticle synthesis can (and should) become a regular occurrence, even in non-specialized labs, facilitating research into their new applications and inspiring outside-the-box solutions, while discussing the drawbacks of a more relaxed synthetic regimen. MDPI 2020-07-10 /pmc/articles/PMC7412208/ /pubmed/32664284 http://dx.doi.org/10.3390/ma13143088 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tabisz, Łukasz
Stanek, Jerzy
Łęska, Bogusława
“DIY” Silica Nanoparticles: Exploring the Scope of a Simplified Synthetic Procedure and Absorbance-Based Diameter Measurements
title “DIY” Silica Nanoparticles: Exploring the Scope of a Simplified Synthetic Procedure and Absorbance-Based Diameter Measurements
title_full “DIY” Silica Nanoparticles: Exploring the Scope of a Simplified Synthetic Procedure and Absorbance-Based Diameter Measurements
title_fullStr “DIY” Silica Nanoparticles: Exploring the Scope of a Simplified Synthetic Procedure and Absorbance-Based Diameter Measurements
title_full_unstemmed “DIY” Silica Nanoparticles: Exploring the Scope of a Simplified Synthetic Procedure and Absorbance-Based Diameter Measurements
title_short “DIY” Silica Nanoparticles: Exploring the Scope of a Simplified Synthetic Procedure and Absorbance-Based Diameter Measurements
title_sort “diy” silica nanoparticles: exploring the scope of a simplified synthetic procedure and absorbance-based diameter measurements
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412208/
https://www.ncbi.nlm.nih.gov/pubmed/32664284
http://dx.doi.org/10.3390/ma13143088
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