Design, Synthesis and Biological Evaluation of Novel Anthraniloyl-AMP Mimics as PQS Biosynthesis Inhibitors Against Pseudomonas aeruginosa Resistance

The Pseudomonas quinolone system (PQS) is one of the three major interconnected quorum sensing signaling systems in Pseudomonas aeruginosa. The virulence factors PQS and HHQ activate the transcription regulator PqsR (MvfR), which controls several activities in bacteria, including biofilm formation a...

Descripción completa

Detalles Bibliográficos
Autores principales: Sabir, Shekh, Subramoni, Sujatha, Das, Theerthankar, Black, David StC., Rice, Scott A., Kumar, Naresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412332/
https://www.ncbi.nlm.nih.gov/pubmed/32646050
http://dx.doi.org/10.3390/molecules25133103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412332/
https://www.ncbi.nlm.nih.gov/pubmed/32646050
http://dx.doi.org/10.3390/molecules25133103

Ejemplares similares