Molecular Features and Metal Ions That Influence 10-23 DNAzyme Activity

Deoxyribozymes (DNAzymes) with RNA hydrolysis activity have a tremendous potential as gene suppression agents for therapeutic applications. The most extensively studied representative is the 10-23 DNAzyme consisting of a catalytic loop and two substrate binding arms that can be designed to bind and...

Descripción completa

Detalles Bibliográficos
Autores principales: Rosenbach, Hannah, Victor, Julian, Etzkorn, Manuel, Steger, Gerhard, Riesner, Detlev, Span, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412337/
https://www.ncbi.nlm.nih.gov/pubmed/32646019
http://dx.doi.org/10.3390/molecules25133100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412337/
https://www.ncbi.nlm.nih.gov/pubmed/32646019
http://dx.doi.org/10.3390/molecules25133100

Ejemplares similares