Cargando…

Circ‐AKT3 inhibits the accumulation of extracellular matrix of mesangial cells in diabetic nephropathy via modulating miR‐296‐3p/E‐cadherin signals

Diabetic nephropathy is a leading cause of end‐stage renal disease globally. The vital role of circular RNAs (circRNAs) has been reported in diabetic nephropathy progression, but the molecular mechanism linking diabetic nephropathy to circRNAs remains elusive. In this study, we investigated the sign...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Bo, Li, Weiliang, Ji, Ting‐Ting, Li, Xiao‐Ying, Qu, Xiaolei, Feng, Linhong, Bai, Shoujun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412430/ https://www.ncbi.nlm.nih.gov/pubmed/32597022 http://dx.doi.org/10.1111/jcmm.15513

Ejemplares similares

Circ-AKT3 inhibits clear cell renal cell carcinoma metastasis via altering miR-296-3p/E-cadherin signals
por: Xue, Dingwei, et al.
Publicado: (2019)

hsa-miR-199b-3p Prevents the Epithelial-Mesenchymal Transition and Dysfunction of the Renal Tubule by Regulating E-cadherin through Targeting KDM6A in Diabetic Nephropathy
por: Bai, Shoujun, et al.
Publicado: (2021)

Loss of lncRNA MIAT ameliorates proliferation and fibrosis of diabetic nephropathy through reducing E2F3 expression
por: Ji, Ting‐Ting, et al.
Publicado: (2020)

Exosomal circ_DLGAP4 promotes diabetic kidney disease progression by sponging miR-143 and targeting ERBB3/NF-κB/MMP-2 axis
por: Bai, Shoujun, et al.
Publicado: (2020)

CircPSMC3 alleviates the symptoms of PCOS by sponging miR‐296‐3p and regulating PTEN expression
por: Liu, Jun, et al.
Publicado: (2020)

Endothelial cells secreted endothelin-1 augments diabetic nephropathy via inducing extracellular matrix accumulation of mesangial cells in ETBR(-/-) mice
por: Zou, Hong-hong, et al.
Publicado: (2019)

Ramipril can alleviate the accumulation of renal mesangial matrix in rats with diabetic nephropathy by inhibiting insulin-like growth factor-1
por: Ren, Wei, et al.
Publicado: (2019)

FOXO3a Protects against Kidney Injury in Type II Diabetic Nephropathy by Promoting Sirt6 Expression and Inhibiting Smad3 Acetylation
por: Wang, Xiaowei, et al.
Publicado: (2021)

AS101 Prevents Diabetic Nephropathy Progression and Mesangial Cell Dysfunction: Regulation of the AKT Downstream Pathway
por: Shemesh, Itay Israel, et al.
Publicado: (2014)

Paeoniflorin Inhibits Mesangial Cell Proliferation and Inflammatory Response in Rats With Mesangial Proliferative Glomerulonephritis Through PI3K/AKT/GSK-3β Pathway
por: Liu, Bihao, et al.
Publicado: (2019)

Pathophysiology of mesangial expansion in diabetic nephropathy: mesangial structure, glomerular biomechanics, and biochemical signaling and regulation
por: Thomas, Haryana Y., et al.
Publicado: (2022)

Berberine regulates mesangial cell proliferation and cell cycle to attenuate diabetic nephropathy through the PI3K/Akt/AS160/GLUT1 signalling pathway
por: Ni, Wei‐Jian, et al.
Publicado: (2022)

Fenofibrate Attenuated Glucose-Induced Mesangial Cells Proliferation and Extracellular Matrix Synthesis via PI3K/AKT and ERK1/2
por: Zeng, Rui, et al.
Publicado: (2013)

Triptolide Suppresses Glomerular Mesangial Cell Proliferation in Diabetic Nephropathy Is Associated with Inhibition of PDK1/Akt/mTOR Pathway
por: Han, Fei, et al.
Publicado: (2017)

CircRNA WHSC1 promotes non‐small cell lung cancer progression via sponging microRNA‐296‐3p and up‐regulating expression of AKT serine/threonine kinase 3
por: Shi, Fengfeng, et al.
Publicado: (2021)

A novel identified circular RNA, circ_0000491, aggravates the extracellular matrix of diabetic nephropathy glomerular mesangial cells through suppressing miR-101b by targeting TGFβRI
por: Mou, Xin, et al.
Publicado: (2020)

XBP1 inhibits mesangial cell apoptosis in response to oxidative stress via the PTEN/AKT pathway in diabetic nephropathy
por: Wang, Yan, et al.
Publicado: (2019)

NAD(+) Anabolism Disturbance Causes Glomerular Mesangial Cell Injury in Diabetic Nephropathy
por: Li, Xue, et al.
Publicado: (2022)

The Influence of a Nanopatterned Scaffold that Mimics Abnormal Renal Mesangial Matrix on Mesangial Cell Behavior
por: Chang, Chia-Jung, et al.
Publicado: (2019)

Warfarin-Related Nephropathy Manifested as Diffuse Mesangial Proliferative Glomerulonephritis
por: Acquah, Frederick, et al.
Publicado: (2022)

Triptolide Suppresses Glomerular Mesangial Cell Proliferation in Diabetic Nephropathy Is Associated with Inhibition of PDK1/Akt/mTOR Pathway: Erratum
por: Han, Fei, et al.
Publicado: (2020)

MicroRNA-296: a promising target in the pathogenesis of atherosclerosis?
por: Li, Heng, et al.
Publicado: (2018)

Decreased Circulating C3 Levels and Mesangial C3 Deposition Predict Renal Outcome in Patients with IgA Nephropathy
por: Kim, Seung Jun, et al.
Publicado: (2012)

Effects of Free Anthraquinones Extract from the Rhubarb on Cell Proliferation and Accumulation of Extracellular Matrix in High Glucose Cultured-Mesangial Cells
por: Wang, Jianyun, et al.
Publicado: (2015)

Exosomal hsa_circ_0125310 promotes cell proliferation and fibrosis in diabetic nephropathy via sponging miR‐422a and targeting the IGF1R/p38 axis
por: Zhu, Yingchun, et al.
Publicado: (2021)

Circular RNA circRUNX1 promotes papillary thyroid cancer progression and metastasis by sponging MiR-296-3p and regulating DDHD2 expression
por: Chu, Junjie, et al.
Publicado: (2021)

Contents of volume 296 (2005)
Publicado: (2005)

Health Tract, No. 296: Hemorrhage
Publicado: (1867)

Ergosterol Ameliorates Diabetic Nephropathy by Attenuating Mesangial Cell Proliferation and Extracellular Matrix Deposition via the TGF-β1/Smad2 Signaling Pathway
por: Dong, Zhonghua, et al.
Publicado: (2019)

Changes in the gene expression programs of renal mesangial cells during diabetic nephropathy
por: Brunskill, Eric W, et al.
Publicado: (2012)

Vorapaxar treatment reduces mesangial expansion in streptozotocin-induced diabetic nephropathy in mice
por: Waasdorp, Maaike, et al.
Publicado: (2018)

Glucosamine inhibits extracellular matrix accumulation in experimental diabetic nephropathy
por: Teuma, Loic, et al.
Publicado: (2022)

Resveratrol Prevention of Diabetic Nephropathy Is Associated with the Suppression of Renal Inflammation and Mesangial Cell Proliferation: Possible Roles of Akt/NF-κB Pathway
por: Xu, Feng, et al.
Publicado: (2014)

LncRNA SOX2OT alleviates mesangial cell proliferation and fibrosis in diabetic nephropathy via Akt/mTOR-mediated autophagy
por: Chen, Ke, et al.
Publicado: (2021)

(Pro)renin receptor is involved in mesangial fibrosis and matrix expansion
por: Narumi, Kaori, et al.
Publicado: (2018)

MDM2 Contributes to High Glucose-Induced Glomerular Mesangial Cell Proliferation and Extracellular Matrix Accumulation via Notch1
por: Lei, Chun-Tao, et al.
Publicado: (2017)

Ganoderic Acid A Inhibits High Glucose-Induced Oxidative Stress and Extracellular Matrix Accumulation in Rat Glomerular Mesangial Cells
por: Wang, Jing, et al.
Publicado: (2022)

Proteomic Identification of 14-3-3ζ as an Adapter for IGF-1 and Akt/GSK-3β Signaling and Survival of Renal Mesangial Cells
por: Singh, Lalit P., et al.
Publicado: (2006)

CircPSMC3 suppresses the proliferation and metastasis of gastric cancer by acting as a competitive endogenous RNA through sponging miR-296-5p
por: Rong, Dawei, et al.
Publicado: (2019)

Aloperine Inhibits Proliferation and Promotes Apoptosis in Colorectal Cancer Cells by Regulating the circNSUN2/miR-296-5p/STAT3 Pathway
por: Han, Wei, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_hoq4s6mqj87ffoklv08jhij1n7