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Functional Reciprocity of Amyloids and Antimicrobial Peptides: Rethinking the Role of Supramolecular Assembly in Host Defense, Immune Activation, and Inflammation

Pathological self-assembly is a concept that is classically associated with amyloids, such as amyloid-β (Aβ) in Alzheimer's disease and α-synuclein in Parkinson's disease. In prokaryotic organisms, amyloids are assembled extracellularly in a similar fashion to human amyloids. Pathogenicity...

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Detalles Bibliográficos
Autores principales: Lee, Ernest Y., Srinivasan, Yashes, de Anda, Jaime, Nicastro, Lauren K., Tükel, Çagla, Wong, Gerard C. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412598/
https://www.ncbi.nlm.nih.gov/pubmed/32849553
http://dx.doi.org/10.3389/fimmu.2020.01629

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