Cargando…
Functional Reciprocity of Amyloids and Antimicrobial Peptides: Rethinking the Role of Supramolecular Assembly in Host Defense, Immune Activation, and Inflammation
Pathological self-assembly is a concept that is classically associated with amyloids, such as amyloid-β (Aβ) in Alzheimer's disease and α-synuclein in Parkinson's disease. In prokaryotic organisms, amyloids are assembled extracellularly in a similar fashion to human amyloids. Pathogenicity...
Autores principales: | Lee, Ernest Y., Srinivasan, Yashes, de Anda, Jaime, Nicastro, Lauren K., Tükel, Çagla, Wong, Gerard C. L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412598/ https://www.ncbi.nlm.nih.gov/pubmed/32849553 http://dx.doi.org/10.3389/fimmu.2020.01629 |
Ejemplares similares
-
Amyloid-containing biofilms and autoimmunity
por: Miller, Amanda L., et al.
Publicado: (2022) -
Phenol-Soluble Modulins From Staphylococcus aureus Biofilms Form Complexes With DNA to Drive Autoimmunity
por: Grando, Kaitlyn, et al.
Publicado: (2022) -
The Functional Amyloid Curli Protects Escherichia coli against Complement-Mediated Bactericidal Activity
por: Biesecker, Steven G., et al.
Publicado: (2018) -
Assembly of ordered DNA-curli fibril complexes during Salmonella biofilm formation correlates with strengths of the type I interferon and autoimmune responses
por: Nicastro, Lauren K., et al.
Publicado: (2022) -
Bacterial amyloid curli acts as a carrier for DNA to elicit an autoimmune response via TLR2 and TLR9
por: Tursi, Sarah A., et al.
Publicado: (2017)