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Overexpression of pyruvate dehydrogenase phosphatase 1 promotes the progression of pancreatic adenocarcinoma by regulating energy-related AMPK/mTOR signaling

BACKGROUND: Human pyruvate dehydrogenase phosphatase 1 (PDP1) plays an important physiological role in energy metabolism; however, its expression and function in human pancreatic adenocarcinoma (PDAC) remain unknown. This study aimed to investigate the expression pattern and mechanisms of action of...

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Detalles Bibliográficos
Autores principales:	Li, Ye, Shen, Jia, Cheng, Chien-shan, Gao, HuiFeng, Zhao, Jiangang, Chen, Lianyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412669/ https://www.ncbi.nlm.nih.gov/pubmed/32782783 http://dx.doi.org/10.1186/s13578-020-00457-5

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