Sotrastaurin, a PKC inhibitor, attenuates RANKL‐induced bone resorption and attenuates osteochondral pathologies associated with the development of OA

Osteoarthritis (OA) is a common degenerative disease that affects the musculoskeletal structure of the whole joint, which is characterized by progressive destruction of both articular cartilage and subchondral bone. Treatment of the bone pathologies, particularly osteoclast‐mediated subchondral bone...

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Detalles Bibliográficos
Autores principales: Pang, Cong, Wen, Liangbao, Qin, Haikuo, Zhu, Bikang, Lu, Xuanyuan, Luo, Shixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412701/
https://www.ncbi.nlm.nih.gov/pubmed/32652826
http://dx.doi.org/10.1111/jcmm.15404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412701/
https://www.ncbi.nlm.nih.gov/pubmed/32652826
http://dx.doi.org/10.1111/jcmm.15404

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