Cargando…
Nomilin targets the Keap1‐Nrf2 signalling and ameliorates the development of osteoarthritis
Osteoarthritis (OA) is a long‐term and inflammatory disorder featured by cartilage erosion. Here, we describe nomilin (NOM), a triterpenoid with inflammation modulatory properties in variety of disorders. In this study, we demonstrated the latent mechanism of NOM in alleviating the progress of OA bo...
Autores principales: | Xue, Xing‐He, Xue, Ji‐Xin, Hu, Wei, Shi, Fang‐Ling, Yang, Yang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412705/ https://www.ncbi.nlm.nih.gov/pubmed/32564468 http://dx.doi.org/10.1111/jcmm.15484 |
Ejemplares similares
-
Deacetylnomilin monohydrate
por: Li, Guo-Qiang, et al.
Publicado: (2011) -
Flos puerariae ameliorates the intestinal inflammation of Drosophila via modulating the Nrf2/Keap1, JAK-STAT and Wnt signaling
por: Yang, Shipei, et al.
Publicado: (2022) -
Zhibaidihuang Decoction Ameliorates Cell Oxidative Stress by Regulating the Keap1-Nrf2-ARE Signalling Pathway
por: Wu, Pingping, et al.
Publicado: (2020) -
Pharmacokinetic and pharmacodynamic drug-drug interaction of Nomilin with atorvastatin in hyperlipidemic mice
por: Ding, Yan, et al.
Publicado: (2023) -
A novel Keap1 inhibitor iKeap1 activates Nrf2 signaling and ameliorates hydrogen peroxide-induced oxidative injury and apoptosis in osteoblasts
por: Zheng, Yue-huan, et al.
Publicado: (2021)