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“Say Ninetynine”: It’s Never Too Late to Recover from COVID-19

COVID-19, the disease caused by severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection, showed higher severity and lethality in male older adults. There are currently no specific treatments. Studies are evaluating the efficacy of monoclonal antibodies against interleukin-6 receptor....

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Autores principales: Tosato, Matteo, Varone, F., Ciccullo, A., Calvani, R., Moschese, D., Potenza, A., Siciliano, M., Fantoni, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412775/
https://www.ncbi.nlm.nih.gov/pubmed/33331625
http://dx.doi.org/10.14283/jfa.2020.41
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author Tosato, Matteo
Varone, F.
Ciccullo, A.
Calvani, R.
Moschese, D.
Potenza, A.
Siciliano, M.
Fantoni, M.
author_facet Tosato, Matteo
Varone, F.
Ciccullo, A.
Calvani, R.
Moschese, D.
Potenza, A.
Siciliano, M.
Fantoni, M.
author_sort Tosato, Matteo
collection PubMed
description COVID-19, the disease caused by severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection, showed higher severity and lethality in male older adults. There are currently no specific treatments. Studies are evaluating the efficacy of monoclonal antibodies against interleukin-6 receptor. Here we present the case of a 98-years old man admitted to our COVID-Hospital with acute respiratory failure. Comprehensive geriatric assessment showed no signs of frailty. First-line therapy with hydroxychloroquine and anticoagulants was not effective. Patient was administered intravenous monoclonal antibodies, and he showed remarkable clinical improvement. This case suggests that age alone should not preclude access to new therapeutic approaches. Comprehensive, multisciplinary, multidomain approaches are needed to develop patient-tailored treatments against COVID-19.
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spelling pubmed-74127752020-08-10 “Say Ninetynine”: It’s Never Too Late to Recover from COVID-19 Tosato, Matteo Varone, F. Ciccullo, A. Calvani, R. Moschese, D. Potenza, A. Siciliano, M. Fantoni, M. J Frailty Aging Case Report COVID-19, the disease caused by severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection, showed higher severity and lethality in male older adults. There are currently no specific treatments. Studies are evaluating the efficacy of monoclonal antibodies against interleukin-6 receptor. Here we present the case of a 98-years old man admitted to our COVID-Hospital with acute respiratory failure. Comprehensive geriatric assessment showed no signs of frailty. First-line therapy with hydroxychloroquine and anticoagulants was not effective. Patient was administered intravenous monoclonal antibodies, and he showed remarkable clinical improvement. This case suggests that age alone should not preclude access to new therapeutic approaches. Comprehensive, multisciplinary, multidomain approaches are needed to develop patient-tailored treatments against COVID-19. Springer International Publishing 2020-08-07 2021 /pmc/articles/PMC7412775/ /pubmed/33331625 http://dx.doi.org/10.14283/jfa.2020.41 Text en © Serdi and Springer Nature Switzerland AG 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Case Report
Tosato, Matteo
Varone, F.
Ciccullo, A.
Calvani, R.
Moschese, D.
Potenza, A.
Siciliano, M.
Fantoni, M.
“Say Ninetynine”: It’s Never Too Late to Recover from COVID-19
title “Say Ninetynine”: It’s Never Too Late to Recover from COVID-19
title_full “Say Ninetynine”: It’s Never Too Late to Recover from COVID-19
title_fullStr “Say Ninetynine”: It’s Never Too Late to Recover from COVID-19
title_full_unstemmed “Say Ninetynine”: It’s Never Too Late to Recover from COVID-19
title_short “Say Ninetynine”: It’s Never Too Late to Recover from COVID-19
title_sort “say ninetynine”: it’s never too late to recover from covid-19
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412775/
https://www.ncbi.nlm.nih.gov/pubmed/33331625
http://dx.doi.org/10.14283/jfa.2020.41
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