Cargando…
The C-terminal region of the oxidoreductase MIA40 stabilizes its cytosolic precursor during mitochondrial import
BACKGROUND: The mitochondrial intermembrane space (IMS) is home to proteins fulfilling numerous essential cellular processes, particularly in metabolism and mitochondrial function. All IMS proteins are nuclear encoded and synthesized in the cytosol and must therefore be correctly targeted and transp...
Autores principales: | Murschall, Lena Maria, Gerhards, Anne, MacVicar, Thomas, Peker, Esra, Hasberg, Lidwina, Wawra, Stephan, Langer, Thomas, Riemer, Jan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412830/ https://www.ncbi.nlm.nih.gov/pubmed/32762682 http://dx.doi.org/10.1186/s12915-020-00824-1 |
Ejemplares similares
-
Increased levels of mitochondrial import factor Mia40 prevent the aggregation of polyQ proteins in the cytosol
por: Schlagowski, Anna M, et al.
Publicado: (2021) -
Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish
por: Sokol, Anna M., et al.
Publicado: (2018) -
Correction: Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish
por: Sokol, Anna M., et al.
Publicado: (2019) -
Mia40-dependent oxidation of cysteines in domain I of Ccs1 controls its distribution between mitochondria and the cytosol
por: Klöppel, Christine, et al.
Publicado: (2011) -
Metabolism and Innate Immunity Meet at the Mitochondria
por: Bahat, Amir, et al.
Publicado: (2021)