Activation and enhancement of caerulomycin A biosynthesis in marine-derived Actinoalloteichus sp. AHMU CJ021 by combinatorial genome mining strategies

BACKGROUND: Activation of silent biosynthetic gene clusters (BGCs) in marine-derived actinomycete strains is a feasible strategy to discover bioactive natural products. Actinoalloteichus sp. AHMU CJ021, isolated from the seashore, was shown to contain an intact but silent caerulomycin A (CRM A) BGC-...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Yunchang, Chen, Jiawen, Wang, Bo, Chen, Tai, Chen, Junyu, Zhang, Yuan, Liu, Xiaoying, Chen, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412835/
https://www.ncbi.nlm.nih.gov/pubmed/32762690
http://dx.doi.org/10.1186/s12934-020-01418-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412835/
https://www.ncbi.nlm.nih.gov/pubmed/32762690
http://dx.doi.org/10.1186/s12934-020-01418-w

Ejemplares similares