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Tanshinone IIA regulates human AML cell proliferation, cell cycle, and apoptosis through miR-497-5p/AKT3 axis

BACKGROUND: The roots of Salvia miltiorrhiza are used in traditional Chinese medicine (TCM) and have high medicinal value. Tanshinone IIA (Tan IIA) is the active ingredient of Salvia miltiorrhiza which can inhibit the growth of acute leukemia cell lines in vitro, although the mechanism remains uncle...

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Detalles Bibliográficos
Autores principales:	Nie, Zi-Yuan, Zhao, Ming-Hui, Cheng, Bao-Qian, Pan, Rong-Fang, Wang, Tian-Rui, Qin, Yan, Zhang, Xue-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412841/ https://www.ncbi.nlm.nih.gov/pubmed/32782437 http://dx.doi.org/10.1186/s12935-020-01468-5

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