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Acute Interstitial Nephritis: A Rare and Unusual Side Effect of Omalizumab
Acute interstitial nephritis (AIN) is a relatively common cause of acute kidney injury with etiologies that include drug therapy, infections, and systemic diseases. Of these etiologies, drug therapy accounts for ~70% of AIN cases. Although any drug can cause AIN, there are no reported cases of AIN c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412888/ https://www.ncbi.nlm.nih.gov/pubmed/32744093 http://dx.doi.org/10.1177/2324709620946890 |
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author | Yang, Rocky Moosavi, Leila Eppanapally, Sabitha Aboeed, Ayham Munoz, Augustine |
author_facet | Yang, Rocky Moosavi, Leila Eppanapally, Sabitha Aboeed, Ayham Munoz, Augustine |
author_sort | Yang, Rocky |
collection | PubMed |
description | Acute interstitial nephritis (AIN) is a relatively common cause of acute kidney injury with etiologies that include drug therapy, infections, and systemic diseases. Of these etiologies, drug therapy accounts for ~70% of AIN cases. Although any drug can cause AIN, there are no reported cases of AIN caused by omalizumab, a humanized monoclonal antibody that binds to and inhibits circulating immunoglobulin E. In this article, we share the first reported case of AIN following administration of omalizumab for the treatment of moderate to severe persistent asthma. |
format | Online Article Text |
id | pubmed-7412888 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-74128882020-08-19 Acute Interstitial Nephritis: A Rare and Unusual Side Effect of Omalizumab Yang, Rocky Moosavi, Leila Eppanapally, Sabitha Aboeed, Ayham Munoz, Augustine J Investig Med High Impact Case Rep Case Report Acute interstitial nephritis (AIN) is a relatively common cause of acute kidney injury with etiologies that include drug therapy, infections, and systemic diseases. Of these etiologies, drug therapy accounts for ~70% of AIN cases. Although any drug can cause AIN, there are no reported cases of AIN caused by omalizumab, a humanized monoclonal antibody that binds to and inhibits circulating immunoglobulin E. In this article, we share the first reported case of AIN following administration of omalizumab for the treatment of moderate to severe persistent asthma. SAGE Publications 2020-08-01 /pmc/articles/PMC7412888/ /pubmed/32744093 http://dx.doi.org/10.1177/2324709620946890 Text en © 2020 American Federation for Medical Research https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Case Report Yang, Rocky Moosavi, Leila Eppanapally, Sabitha Aboeed, Ayham Munoz, Augustine Acute Interstitial Nephritis: A Rare and Unusual Side Effect of Omalizumab |
title | Acute Interstitial Nephritis: A Rare and Unusual Side Effect of Omalizumab |
title_full | Acute Interstitial Nephritis: A Rare and Unusual Side Effect of Omalizumab |
title_fullStr | Acute Interstitial Nephritis: A Rare and Unusual Side Effect of Omalizumab |
title_full_unstemmed | Acute Interstitial Nephritis: A Rare and Unusual Side Effect of Omalizumab |
title_short | Acute Interstitial Nephritis: A Rare and Unusual Side Effect of Omalizumab |
title_sort | acute interstitial nephritis: a rare and unusual side effect of omalizumab |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412888/ https://www.ncbi.nlm.nih.gov/pubmed/32744093 http://dx.doi.org/10.1177/2324709620946890 |
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