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Effect of Concentration/Dose Ratio in De Novo Kidney Transplant Recipients Receiving LCP-Tacrolimus or Immediate-Release Tacrolimus: Post Hoc Analysis of a Phase 3 Clinical Trial

BACKGROUND: A previous phase 3 clinical trial in de novo adult kidney transplant recipients (NCT01187953) compared the efficacy and safety of once-daily LCP-tacrolimus (LCPT) and twice-daily immediate-release tacrolimus (IR-Tac). However, whether the rate of tacrolimus metabolism affects outcomes be...

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Detalles Bibliográficos
Autores principales: Suwelack, Barbara, Bunnapradist, Suphamai, Meier-Kriesche, Ulf, Stevens, Daniel R., Procaccianti, Claudio, Morganti, Roberto, Budde, Klemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412936/
https://www.ncbi.nlm.nih.gov/pubmed/32719307
http://dx.doi.org/10.12659/AOT.923278