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Automated and rapid self-report of nociception in transgenic mice
There are currently no rapid, operant pain behaviors in rodents that use a self-report to directly engage higher-order brain circuitry. We have developed a pain detection assay consisting of a lick behavior in response to optogenetic activation of predominantly nociceptive peripheral afferent nerve...
Autores principales: | Black, Christopher J., Allawala, Anusha B., Bloye, Kiernan, Vanent, Kevin N., Edhi, Muhammad M., Saab, Carl Y., Borton, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413385/ https://www.ncbi.nlm.nih.gov/pubmed/32764714 http://dx.doi.org/10.1038/s41598-020-70028-8 |
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