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Automated and rapid self-report of nociception in transgenic mice

There are currently no rapid, operant pain behaviors in rodents that use a self-report to directly engage higher-order brain circuitry. We have developed a pain detection assay consisting of a lick behavior in response to optogenetic activation of predominantly nociceptive peripheral afferent nerve...

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Detalles Bibliográficos
Autores principales: Black, Christopher J., Allawala, Anusha B., Bloye, Kiernan, Vanent, Kevin N., Edhi, Muhammad M., Saab, Carl Y., Borton, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413385/
https://www.ncbi.nlm.nih.gov/pubmed/32764714
http://dx.doi.org/10.1038/s41598-020-70028-8

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