Cargando…

Zuo1 supports G4 structure formation and directs repair toward nucleotide excision repair

Nucleic acids can fold into G-quadruplex (G4) structures that can fine-tune biological processes. Proteins are required to recognize G4 structures and coordinate their function. Here we identify Zuo1 as a novel G4-binding protein in vitro and in vivo. In vivo in the absence of Zuo1 fewer G4 structur...

Descripción completa

Detalles Bibliográficos
Autores principales: De Magis, Alessio, Götz, Silvia, Hajikazemi, Mona, Fekete-Szücs, Enikő, Caterino, Marco, Juranek, Stefan, Paeschke, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413387/
https://www.ncbi.nlm.nih.gov/pubmed/32764578
http://dx.doi.org/10.1038/s41467-020-17701-8