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Zuo1 supports G4 structure formation and directs repair toward nucleotide excision repair
Nucleic acids can fold into G-quadruplex (G4) structures that can fine-tune biological processes. Proteins are required to recognize G4 structures and coordinate their function. Here we identify Zuo1 as a novel G4-binding protein in vitro and in vivo. In vivo in the absence of Zuo1 fewer G4 structur...
Autores principales: | De Magis, Alessio, Götz, Silvia, Hajikazemi, Mona, Fekete-Szücs, Enikő, Caterino, Marco, Juranek, Stefan, Paeschke, Katrin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413387/ https://www.ncbi.nlm.nih.gov/pubmed/32764578 http://dx.doi.org/10.1038/s41467-020-17701-8 |
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