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Molecular magnetic resonance imaging of activated platelets allows noninvasive detection of early myocarditis in mice

MRI sensitivity for diagnosis and localization of early myocarditis is limited, although it is of central clinical interest. The aim of this project was to test a contrast agent targeting activated platelets consisting of microparticles of iron oxide (MPIO) conjugated to a single-chain antibody dire...

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Detalles Bibliográficos
Autores principales: Maier, Alexander, Braig, Moritz, Jakob, Katharina, Bienert, Thomas, Schäper, Michaela, Merkle, Annette, Wadle, Carolin, Menza, Marius, Neudorfer, Irene, Bojti, István, Stachon, Peter, Duerschmied, Daniel, Hilgendorf, Ingo, Heidt, Timo, Bode, Christoph, Peter, Karlheinz, Klingel, Karin, von Elverfeldt, Dominik, von zur Mühlen, Constantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413393/
https://www.ncbi.nlm.nih.gov/pubmed/32764735
http://dx.doi.org/10.1038/s41598-020-70043-9