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AhR-activating pesticides increase the bovine ABCG2 efflux activity in MDCKII-bABCG2 cells

In bovine mammary glands, the ABCG2 transporter actively secretes xenobiotics into dairy milk. This can have significant implications when cattle are exposed to pesticide residues in feed. Recent studies indicate that the fungicide prochloraz activates the aryl hydrocarbon receptor (AhR) pathway, in...

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Detalles Bibliográficos
Autores principales:	Kuhnert, Lydia, Giantin, Mery, Dacasto, Mauro, Halwachs, Sandra, Honscha, Walther
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413513/ https://www.ncbi.nlm.nih.gov/pubmed/32764792 http://dx.doi.org/10.1371/journal.pone.0237163

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