Cargando…

Notch and TLR signaling coordinate monocyte cell fate and inflammation

Conventional Ly6C(hi) monocytes have developmental plasticity for a spectrum of differentiated phagocytes. Here we show, using conditional deletion strategies in a mouse model of Toll-like receptor (TLR) 7-induced inflammation, that the spectrum of developmental cell fates of Ly6C(hi) monocytes, and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gamrekelashvili, Jaba, Kapanadze, Tamar, Sablotny, Stefan, Ratiu, Corina, Dastagir, Khaled, Lochner, Matthias, Karbach, Susanne, Wenzel, Philip, Sitnow, Andre, Fleig, Susanne, Sparwasser, Tim, Kalinke, Ulrich, Holzmann, Bernhard, Haller, Hermann, Limbourg, Florian P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413669/ https://www.ncbi.nlm.nih.gov/pubmed/32723480 http://dx.doi.org/10.7554/eLife.57007

Ejemplares similares

CSF-1 and Notch signaling cooperate in macrophage instruction and tissue repair during peripheral limb ischemia
por: Kapanadze, Tamar, et al.
Publicado: (2023)

A new fasciocutaneous flap model identifies a critical role for endothelial Notch signaling in wound healing and flap survival
por: Dastagir, Khaled, et al.
Publicado: (2023)

Regulation of monocyte cell fate by blood vessels mediated by Notch signalling
por: Gamrekelashvili, Jaba, et al.
Publicado: (2016)

The chemokine receptor CX (3) CR1 coordinates monocyte recruitment and endothelial regeneration after arterial injury
por: Getzin, Tobias, et al.
Publicado: (2017)

Corrigendum: Regulation of monocyte cell fate by blood vessels mediated by Notch signalling
por: Gamrekelashvili, Jaba, et al.
Publicado: (2017)

Retinal myeloid cells regulate tip cell selection and vascular branching morphogenesis via Notch ligand Delta-like 1
por: Haupt, Fabian, et al.
Publicado: (2019)

Loss of vascular endothelial notch signaling promotes spontaneous formation of tertiary lymphoid structures
por: Fleig, Susanne, et al.
Publicado: (2022)

Multimodal and Multiscale Analysis Reveals Distinct Vascular, Metabolic and Inflammatory Components of the Tissue Response to Limb Ischemia
por: Kapanadze, Tamar, et al.
Publicado: (2019)

Blood vessel control of macrophage maturation promotes arteriogenesis in ischemia
por: Krishnasamy, Kashyap, et al.
Publicado: (2017)

Effectiveness of a Fixed-Dose, Single-Pill Combination of Perindopril and Amlodipine in Patients with Hypertension: A Non-Interventional Study
por: Fleig, Susanne V., et al.
Publicado: (2018)

Dipeptidyl peptidase 3 and thimet oligopeptidase 1 knockdown support tumor-specific immune responses to whole cell cancer vaccines and tumor cell death in vivo
por: Gamrekelashvili, Jaba, et al.
Publicado: (2013)

Fate mapping analysis reveals a novel murine dermal migratory Langerhans-like cell population
por: Sheng, Jianpeng, et al.
Publicado: (2021)

SMAD4 and TGFβ are architects of inverse genetic programs during fate determination of antiviral CTLs
por: Chandiran, Karthik, et al.
Publicado: (2022)

IgM and IgD B cell receptors differentially respond to endogenous antigens and control B cell fate
por: Noviski, Mark, et al.
Publicado: (2018)

Blood flow controls bone vascular function and osteogenesis
por: Ramasamy, Saravana K., et al.
Publicado: (2016)

Human Th17 cells in patients with cancer: Friends or foe?
por: Greten, Tim F., et al.
Publicado: (2012)

Loss of GTPase activating protein neurofibromin stimulates paracrine cell communication via macropinocytosis
por: Ghoshal, Pushpankur, et al.
Publicado: (2019)

Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4(+) and CD8(+) T-lymphocytes
por: Moshfegh, C.M., et al.
Publicado: (2019)

Role of Inflammation in Coronary Epicardial and Microvascular Dysfunction
por: Godo, Shigeo, et al.
Publicado: (2021)

Anti-inflammatory Treatment and Cardiovascular Outcomes: Results of Clinical Trials
por: Lorenzatti, Alberto J
Publicado: (2021)

Atherosclerotic Cardiovascular Disease in Rheumatoid Arthritis: Impact of Inflammation and Antirheumatic Treatment
por: Kerola, Anne Mirjam, et al.
Publicado: (2021)

The Role of C-reactive Protein in Patient Risk Stratification and Treatment
por: Arroyo-Espliguero, Ramón, et al.
Publicado: (2021)

Inflammation and Cardiovascular Disease: The Future
por: Arnold, Natalie, et al.
Publicado: (2021)

Small bowel stomas are associated with higher risk of circulating food-specific-IgG than patients with organic gastrointestinal conditions and colostomies
por: Carson, Walker K, et al.
Publicado: (2022)

Kynurenine pathway is altered in patients with SLE and associated with severe fatigue
por: Åkesson, Karolina, et al.
Publicado: (2018)

Single-cell profiling reveals periventricular CD56(bright) NK cell accumulation in multiple sclerosis
por: Rodríguez-Lorenzo, Sabela, et al.
Publicado: (2022)

Hepatic myeloid-derived suppressor cells in tumor bearing mice exacerbate hepatitis and transform into pro-inflammatory myeloid cells
por: Medina-Echeverz, Jose, et al.
Publicado: (2013)

Identification of specific Tie2 cleavage sites and therapeutic modulation in experimental sepsis
por: Idowu, Temitayo O, et al.
Publicado: (2020)

TLR7 activation at epithelial barriers promotes emergency myelopoiesis and lung antiviral immunity
por: Jackson, William D, et al.
Publicado: (2023)

Loss of Mef2D function enhances TLR induced IL-10 production in macrophages
por: Pattison, Michael J., et al.
Publicado: (2020)

Mycobacterium tuberculosis canonical virulence factors interfere with a late component of the TLR2 response
por: Hinman, Amelia E, et al.
Publicado: (2021)

TAK1 protein kinase activity is required for TLR signalling and cytokine production in myeloid cells
por: Rodrigues, Melissa, et al.
Publicado: (2022)

Erythropoietin directly remodels the clonal composition of murine hematopoietic multipotent progenitor cells
por: Eisele, Almut S, et al.
Publicado: (2022)

Airway epithelial TSLP production of TLR2 drives type 2 immunity in allergic airway inflammation
por: Lv, Jiajia, et al.
Publicado: (2018)

TLR induces reorganization of the IgM-BCR complex regulating murine B-1 cell responses to infections
por: Savage, Hannah P, et al.
Publicado: (2019)

Domain fusion TLR2-4 enhances the autophagy-dependent clearance of Staphylococcus aureus in the genetic engineering goat
por: Wang, Mengyao, et al.
Publicado: (2022)

Atmospheric particulate matter aggravates CNS demyelination through involvement of TLR-4/NF-kB signaling and microglial activation
por: Han, Bing, et al.
Publicado: (2022)

Silencing of PTX3 alleviates LPS-induced inflammatory pain by regulating TLR4/NF-κB signaling pathway in mice
por: Qi, Shuang, et al.
Publicado: (2020)

SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-κB pathway
por: Khan, Shahanshah, et al.
Publicado: (2021)

Identification of ester-linked ubiquitylation sites during TLR7 signalling increases the number of inter-ubiquitin linkages from 8 to 12
por: McCrory, Elisha H., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hgrlu7e0roaa6u3a6bgk3aou0t