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Tailoring B cell depletion therapy in MS according to memory B cell monitoring

OBJECTIVE: We wanted to evaluate efficacy on inflammatory parameters of rituximab (RTX)-personalized reinfusion scheme using a memory B cell–based treatment regimen. METHODS: This is a prospective, uncontrolled, open-label study including patients with MS treated with RTX in 2 Italian MS units. All...

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Detalles Bibliográficos
Autores principales: Novi, Giovanni, Bovis, Francesca, Fabbri, Sabrina, Tazza, Francesco, Gazzola, Paola, Maietta, Ilaria, Currò, Daniela, Bruschi, Nicolò, Roccatagliata, Luca, Boffa, Giacomo, Lapucci, Caterina, Pesce, Giampaola, Cellerino, Maria, Solaro, Claudio, Laroni, Alice, Capello, Elisabetta, Mancardi, Gianluigi, Sormani, Mariapia, Inglese, Matilde, Uccelli, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413707/
https://www.ncbi.nlm.nih.gov/pubmed/32753406
http://dx.doi.org/10.1212/NXI.0000000000000845