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Effect of the sphingosine-1-phosphate receptor modulator ozanimod on leukocyte subtypes in relapsing MS

OBJECTIVE: To better understand ozanimod's mechanism of action (MOA), we conducted exploratory analyses from a phase 1 study to characterize ozanimod's effect on circulating leukocyte subsets in patients with relapsing multiple sclerosis. METHODS: An open-label pharmacodynamic study random...

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Detalles Bibliográficos
Autores principales: Harris, Sarah, Tran, Jonathan Q., Southworth, Harry, Spencer, Collin M., Cree, Bruce A.C., Zamvil, Scott S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413711/
https://www.ncbi.nlm.nih.gov/pubmed/32737072
http://dx.doi.org/10.1212/NXI.0000000000000839