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Phosphoribosyl Pyrophosphate Amidotransferase Promotes the Progression of Thyroid Cancer via Regulating Pyruvate Kinase M2

BACKGROUND: Pyruvate kinase is an enzyme that catalyzes the conversion of phosphoenolpyruvate and ADP to pyruvate and ATP in glycolysis and plays a role in regulating cell metabolism. It is reported that the activity of pyruvate kinase is increased in cancers. Phosphoribosyl amidotransferase (PPAT)...

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Detalles Bibliográficos
Autores principales:	Liu, Bing, Song, Meiyue, Qin, Huadong, Zhang, Bin, Liu, Yao, Sun, Yu, Ma, Yanfei, Shi, Tiefeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413720/ https://www.ncbi.nlm.nih.gov/pubmed/32801776 http://dx.doi.org/10.2147/OTT.S253137

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