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Adjuvant-free nanofiber vaccine induces in situ lung dendritic cell activation and T(H)17 responses
The current paradigm that subunit vaccines require adjuvants to optimally activate innate immunity implies that increased vaccine reactogenicity will invariably be linked to improved immunogenicity. Countering this paradigm, nanoparticulate vaccines have been reported to act as delivery systems for...
Autores principales: | Si, Youhui, Tian, Qiaomu, Zhao, Fan, Kelly, Sean H., Shores, Lucas S., Camacho, Daniel F., Sperling, Anne I., Andrade, Michael S., Collier, Joel H., Chong, Anita S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413739/ https://www.ncbi.nlm.nih.gov/pubmed/32821819 http://dx.doi.org/10.1126/sciadv.aba0995 |
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