Mitochondrial DNA enhance innate immune responses in neuromyelitis optica by monocyte recruitment and activation

Although recent studies indicate the involvement of monocytes in accelerating the lesion formation of neuromyelitis optica spectrum disorder (NMOSD), the precise mechanism of the innate immune system activation remains elusive. Thus, in this study, we aimed to clarify the mechanisms of NMOSD pathoge...

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Detalles Bibliográficos
Autores principales: Shimizu, Mikito, Okuno, Tatsusada, Kinoshita, Makoto, Sumi, Hisae, Fujimura, Harutoshi, Yamashita, Kazuya, Sugimoto, Tomoyuki, Sakakibara, Shuhei, Sakakibara, Kaori, Koda, Toru, Tada, Satoru, Ishikura, Teruyuki, Murata, Hisashi, Beppu, Shohei, Shiraishi, Naoyuki, Sugiyama, Yasuko, Nakatsuji, Yuji, Kumanogoh, Atsushi, Mochizuki, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414017/
https://www.ncbi.nlm.nih.gov/pubmed/32764561
http://dx.doi.org/10.1038/s41598-020-70203-x

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