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Identification of GLUT12/SLC2A12 as a urate transporter that regulates the blood urate level in hyperuricemia model mice
Recent genome-wide association studies have revealed some genetic loci associated with serum uric acid levels and susceptibility to gout/hyperuricemia which contain potential candidates of physiologically important urate transporters. One of these novel loci is located upstream of SGK1 and SLC2A12,...
Autores principales: | Toyoda, Yu, Takada, Tappei, Miyata, Hiroshi, Matsuo, Hirotaka, Kassai, Hidetoshi, Nakao, Kazuki, Nakatochi, Masahiro, Kawamura, Yusuke, Shimizu, Seiko, Shinomiya, Nariyoshi, Ichida, Kimiyoshi, Hosoyamada, Makoto, Aiba, Atsu, Suzuki, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414087/ https://www.ncbi.nlm.nih.gov/pubmed/32690690 http://dx.doi.org/10.1073/pnas.2006958117 |
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