Epsin-mediated degradation of IP3R1 fuels atherosclerosis

The epsin family of endocytic adapter proteins are widely expressed, and interact with both proteins and lipids to regulate a variety of cell functions. However, the role of epsins in atherosclerosis is poorly understood. Here, we show that deletion of endothelial epsin proteins reduces inflammation...

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Detalles Bibliográficos
Autores principales: Dong, Yunzhou, Lee, Yang, Cui, Kui, He, Ming, Wang, Beibei, Bhattacharjee, Sudarshan, Zhu, Bo, Yago, Tadayuki, Zhang, Kun, Deng, Lin, Ouyang, Kunfu, Wen, Aiyun, Cowan, Douglas B., Song, Kai, Yu, Lili, Brophy, Megan L., Liu, Xiaolei, Wylie-Sears, Jill, Wu, Hao, Wong, Scott, Cui, Guanglin, Kawashima, Yusuke, Matsumoto, Hiroyuki, Kodera, Yoshio, Wojcikiewicz, Richard J. H., Srivastava, Sanjay, Bischoff, Joyce, Wang, Da-Zhi, Ley, Klaus, Chen, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414107/
https://www.ncbi.nlm.nih.gov/pubmed/32770009
http://dx.doi.org/10.1038/s41467-020-17848-4

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