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Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase

Mevalonate diphosphate decarboxylases (MDDs) catalyze the ATP-dependent-Mg(2+)-decarboxylation of mevalonate-5-diphosphate (MVAPP) to produce isopentenyl diphosphate (IPP), which is essential in both eukaryotes and prokaryotes for polyisoprenoid synthesis. The substrates, MVAPP and ATP, have been sh...

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Detalles Bibliográficos
Autores principales:	Chen, Chun-Liang, Paul, Lake N., Mermoud, James C., Steussy, Calvin Nicklaus, Stauffacher, Cynthia V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414129/ https://www.ncbi.nlm.nih.gov/pubmed/32769976 http://dx.doi.org/10.1038/s41467-020-17733-0

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