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HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer

Methionine restriction, a dietary regimen that protects against metabolic diseases and aging, represses cancer growth and improves cancer therapy. However, the response of different cancer cells to this nutritional manipulation is highly variable, and the molecular determinants of this heterogeneity...

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Detalles Bibliográficos
Autores principales:	Xu, Qing, Li, Yuanyuan, Gao, Xia, Kang, Kai, Williams, Jason G., Tong, Lingfeng, Liu, Juan, Ji, Ming, Deterding, Leesa J., Tong, Xuemei, Locasale, Jason W., Li, Leping, Shats, Igor, Li, Xiaoling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414133/ https://www.ncbi.nlm.nih.gov/pubmed/32770044 http://dx.doi.org/10.1038/s41467-020-17818-w

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