Cargando…

Transcriptomic analysis delineates potential signature genes and miRNAs associated with the pathogenesis of asthma

Asthma is a multifarious disease affecting several million people around the world. It has a heterogeneous risk architecture inclusive of both genetic and environmental factors. This heterogeneity can be utilised to identify differentially expressed biomarkers of the disease, which may ultimately ai...

Descripción completa

Detalles Bibliográficos
Autores principales:	Singh, Prithvi, Sharma, Archana, Jha, Rishabh, Arora, Shweta, Ahmad, Rafiq, Rahmani, Arshad Husain, Almatroodi, Saleh A., Dohare, Ravins, Syed, Mansoor Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414199/ https://www.ncbi.nlm.nih.gov/pubmed/32770056 http://dx.doi.org/10.1038/s41598-020-70368-5

Ejemplares similares

Unravelling the Role of miR-20b-5p, CCNB1, HMGA2 and E2F7 in Development and Progression of Non-Small Cell Lung Cancer (NSCLC)
por: Arora, Shweta, et al.
Publicado: (2020)

Inhibition of miRNA-34a Promotes M2 Macrophage Polarization and Improves LPS-Induced Lung Injury by Targeting Klf4
por: Khan, Mohd Junaid, et al.
Publicado: (2020)

Exploring the role of miR-200 family in regulating CX3CR1 and CXCR1 in lung adenocarcinoma tumor microenvironment: implications for therapeutic intervention
por: Sharma, Archana, et al.
Publicado: (2023)

Transcriptome Meta-Analysis Deciphers a Dysregulation in Immune Response-Associated Gene Signatures during Sepsis
por: Ahmad, Shaniya, et al.
Publicado: (2019)

Comprehensive Integrative Analysis Reveals the Association of KLF4 with Macrophage Infiltration and Polarization in Lung Cancer Microenvironment
por: Arora, Shweta, et al.
Publicado: (2021)

Unravelling host-pathogen interactions: ceRNA network in SARS-CoV-2 infection (COVID-19)
por: Arora, Shweta, et al.
Publicado: (2020)

Integrated transcriptomic and regulatory network analyses uncovers the role of let-7b-5p, SPIB, and HLA-DPB1 in sepsis
por: Mohsin, Mohd, et al.
Publicado: (2022)

Combined Multiomics and In Silico Approach Uncovers PRKAR1A as a Putative Therapeutic Target in Multi-Organ Dysfunction Syndrome
por: Singh, Prithvi, et al.
Publicado: (2023)

Survival-Based Biomarker Module Identification Associated with Oral Squamous Cell Carcinoma (OSCC)
por: Singh, Prithvi, et al.
Publicado: (2021)

Network-based identification of signature genes KLF6 and SPOCK1 associated with oral submucous fibrosis
por: Singh, Prithvi, et al.
Publicado: (2020)

Identification of differentially expressed genes in small and non-small cell lung cancer based on meta-analysis of mRNA
por: Shriwash, Nitesh, et al.
Publicado: (2019)

Integrative Multiomics and Regulatory Network Analyses Uncovers the Role of OAS3, TRAFD1, miR-222-3p, and miR-125b-5p in Hepatitis E Virus Infection
por: Gupta, Sonam, et al.
Publicado: (2022)

Epigallocatechin-3-Gallate (EGCG), an Active Compound of Green Tea Attenuates Acute Lung Injury Regulating Macrophage Polarization and Krüpple-Like-Factor 4 (KLF4) Expression
por: Almatroodi, Saleh A., et al.
Publicado: (2020)

Berberine: An Important Emphasis on Its Anticancer Effects through Modulation of Various Cell Signaling Pathways
por: Almatroodi, Saleh A., et al.
Publicado: (2022)

Potential Therapeutic Targets of Formononetin, a Type of Methoxylated Isoflavone, and Its Role in Cancer Therapy through the Modulation of Signal Transduction Pathways
por: Almatroodi, Saleh A., et al.
Publicado: (2023)

Correlation of NTRK1 Downregulation with Low Levels of Tumor-Infiltrating Immune Cells and Poor Prognosis of Prostate Cancer Revealed by Gene Network Analysis
por: Bagherabadi, Arash, et al.
Publicado: (2022)

Quercetin, a Plant Flavonol Attenuates Diabetic Complications, Renal Tissue Damage, Renal Oxidative Stress and Inflammation in Streptozotocin-Induced Diabetic Rats
por: Rahmani, Arshad Husain, et al.
Publicado: (2023)

The Potential Role of Fisetin, a Flavonoid in Cancer Prevention and Treatment
por: Rahmani, Arshad Husain, et al.
Publicado: (2022)

Protective Effects of Thymoquinone, an Active Compound of Nigella sativa, on Rats with Benzo(a)pyrene-Induced Lung Injury through Regulation of Oxidative Stress and Inflammation
por: Alzohairy, Mohammad A., et al.
Publicado: (2021)

Investigating the role of Kinesin family in lung adenocarcinoma via integrated bioinformatics approach
por: Tabassum, Gulnaz, et al.
Publicado: (2023)

Prognostic Significance of Vascular Endothelial Growth Factor (VEGF) and Her-2 Protein in the Genesis of Cervical Carcinoma
por: Rahmani, Arshad H., et al.
Publicado: (2018)

Curcumin, an Active Constituent of Turmeric Spice: Implication in the Prevention of Lung Injury Induced by Benzo(a) Pyrene (BaP) in Rats
por: Almatroodi, Saleh A., et al.
Publicado: (2020)

Potential Antitumor Effects of Pomegranates and Its Ingredients
por: Rahmani, Arshad H., et al.
Publicado: (2017)

Potential Therapeutic Targets of Epigallocatechin Gallate (EGCG), the Most Abundant Catechin in Green Tea, and Its Role in the Therapy of Various Types of Cancer
por: Almatroodi, Saleh A., et al.
Publicado: (2020)

Differential Gene Expression and Weighted Correlation Network Dynamics in High-Throughput Datasets of Prostate Cancer
por: Mohammad, Taj, et al.
Publicado: (2022)

Endoplasmic Reticulum Stress Provocation by Different Nanoparticles: An Innovative Approach to Manage the Cancer and Other Common Diseases
por: Khan, Amjad Ali, et al.
Publicado: (2020)

6-Gingerol, a Bioactive Compound of Ginger Attenuates Renal Damage in Streptozotocin-Induced Diabetic Rats by Regulating the Oxidative Stress and Inflammation
por: Almatroodi, Saleh A., et al.
Publicado: (2021)

Mathematical modeling in perspective of vector-borne viral infections: a review
por: Prasad, Ramakant, et al.
Publicado: (2022)

The Potential Role of Apigenin in Cancer Prevention and Treatment
por: Rahmani, Arshad Husain, et al.
Publicado: (2022)

SMAC Mimetic BV6 Co-Treatment Downregulates the Factors Involved in Resistance and Relapse of Cancer: IAPs and Autophagy
por: Rafat, Sahar, et al.
Publicado: (2022)

Potential Therapeutic Targets of Quercetin, a Plant Flavonol, and Its Role in the Therapy of Various Types of Cancer through the Modulation of Various Cell Signaling Pathways
por: Almatroodi, Saleh A., et al.
Publicado: (2021)

Novel Approaches of Dysregulating Lysosome Functions in Cancer Cells by Specific Drugs and Its Nanoformulations: A Smart Approach of Modern Therapeutics
por: Allemailem, Khaled S, et al.
Publicado: (2021)

6-Gingerol, a Major Ingredient of Ginger Attenuates Diethylnitrosamine-Induced Liver Injury in Rats through the Modulation of Oxidative Stress and Anti-Inflammatory Activity
por: Alsahli, Mohammed A., et al.
Publicado: (2021)

Potential Therapeutic Targets of Resveratrol, a Plant Polyphenol, and Its Role in the Therapy of Various Types of Cancer
por: Almatroodi, Saleh A., et al.
Publicado: (2022)

Myricetin: A Significant Emphasis on Its Anticancer Potential via the Modulation of Inflammation and Signal Transduction Pathways
por: Rahmani, Arshad Husain, et al.
Publicado: (2023)

Effects and Mechanisms of Kaempferol in the Management of Cancers through Modulation of Inflammation and Signal Transduction Pathways
por: Almatroudi, Ahmad, et al.
Publicado: (2023)

Evolutionary Analysis of Dengue Serotype 2 Viruses Using Phylogenetic and Bayesian Methods from New Delhi, India
por: Afreen, Nazia, et al.
Publicado: (2016)

Regulation of Pro-Inflammatory Macrophage Polarization via Lipid Nanoparticles Mediated Delivery of Anti-Prostaglandin-E2 siRNA
por: Almatroudi, Ahmad, et al.
Publicado: (2022)

Delineating asthma according to inflammation phenotypes with a focus on paucigranulocytic asthma
por: Feng, Yinhe, et al.
Publicado: (2023)

Role of Ajwa Date Fruit Pulp and Seed in the Management of Diseases through In Vitro and In Silico Analysis
por: Anwar, Shehwaz, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_99so8ittgfb404j2h89j84j6f2