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Changes in CT manifestations and RT-PCR testings of the coronavirus disease 2019 until recovery in patients with afferent infection vs. second-generation infection outside the original city (Wuhan): An observational study

OBJECTIVE: To investigate changes in CT manifestations and results of reverse transcription polymerase chain reaction (RT-PCR) testing between afferent and second-generation coronavirus disease 2019 (COVID-19) outside the original city (Wuhan) until recovery. METHODS: We collected 26 consecutive COV...

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Autores principales: Tang, Sun, Ou, Jing, Li, Rui, Zhang, Xiaoming, Chen, Tian wu, Li, Hongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beijing You'an Hospital affiliated to Capital Medical University. Production and hosting by Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414381/
https://www.ncbi.nlm.nih.gov/pubmed/32838010
http://dx.doi.org/10.1016/j.jrid.2020.07.007
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author Tang, Sun
Ou, Jing
Li, Rui
Zhang, Xiaoming
Chen, Tian wu
Li, Hongjun
author_facet Tang, Sun
Ou, Jing
Li, Rui
Zhang, Xiaoming
Chen, Tian wu
Li, Hongjun
author_sort Tang, Sun
collection PubMed
description OBJECTIVE: To investigate changes in CT manifestations and results of reverse transcription polymerase chain reaction (RT-PCR) testing between afferent and second-generation coronavirus disease 2019 (COVID-19) outside the original city (Wuhan) until recovery. METHODS: We collected 26 consecutive COVID-19 patients undergoing initial and follow-up CT scans together with RT-PCR until recovery from 2 hospitals outside the original city. Seventeen patients with afferent infection and 9 with second-generation infection were assigned to Group A and B, respectively. By observing CT manifestations, we scored COVID-19, and statistically analyzed numbers of patients with changes in CT scores and RT-PCR results between stages. RESULTS: The total score of COVID-19 on initial CT manifestations was higher in Group A than in Group B (P < 0.05). COVID-19 progressed more frequently from stage 1–2, and relieved from stage 3–4 in Group A (P < 0.05). The similar trend in Group A could not be found in Group B. Results of RT-PCR in most of patients in Group A turned negative at stage 4 while those in Group B turned negative at stage 3 (P < 0.05). CONCLUSION: Changes in CT manifestation and RT-PCR result can be different between afferent and second-generation COVID-19 until recovery.
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spelling pubmed-74143812020-08-10 Changes in CT manifestations and RT-PCR testings of the coronavirus disease 2019 until recovery in patients with afferent infection vs. second-generation infection outside the original city (Wuhan): An observational study Tang, Sun Ou, Jing Li, Rui Zhang, Xiaoming Chen, Tian wu Li, Hongjun Radiol Infect Dis Research Article OBJECTIVE: To investigate changes in CT manifestations and results of reverse transcription polymerase chain reaction (RT-PCR) testing between afferent and second-generation coronavirus disease 2019 (COVID-19) outside the original city (Wuhan) until recovery. METHODS: We collected 26 consecutive COVID-19 patients undergoing initial and follow-up CT scans together with RT-PCR until recovery from 2 hospitals outside the original city. Seventeen patients with afferent infection and 9 with second-generation infection were assigned to Group A and B, respectively. By observing CT manifestations, we scored COVID-19, and statistically analyzed numbers of patients with changes in CT scores and RT-PCR results between stages. RESULTS: The total score of COVID-19 on initial CT manifestations was higher in Group A than in Group B (P < 0.05). COVID-19 progressed more frequently from stage 1–2, and relieved from stage 3–4 in Group A (P < 0.05). The similar trend in Group A could not be found in Group B. Results of RT-PCR in most of patients in Group A turned negative at stage 4 while those in Group B turned negative at stage 3 (P < 0.05). CONCLUSION: Changes in CT manifestation and RT-PCR result can be different between afferent and second-generation COVID-19 until recovery. Beijing You'an Hospital affiliated to Capital Medical University. Production and hosting by Elsevier B.V. 2020-09 2020-08-08 /pmc/articles/PMC7414381/ /pubmed/32838010 http://dx.doi.org/10.1016/j.jrid.2020.07.007 Text en © 2020 Beijing You'an Hospital affiliated to Capital Medical University. Production and hosting by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Research Article
Tang, Sun
Ou, Jing
Li, Rui
Zhang, Xiaoming
Chen, Tian wu
Li, Hongjun
Changes in CT manifestations and RT-PCR testings of the coronavirus disease 2019 until recovery in patients with afferent infection vs. second-generation infection outside the original city (Wuhan): An observational study
title Changes in CT manifestations and RT-PCR testings of the coronavirus disease 2019 until recovery in patients with afferent infection vs. second-generation infection outside the original city (Wuhan): An observational study
title_full Changes in CT manifestations and RT-PCR testings of the coronavirus disease 2019 until recovery in patients with afferent infection vs. second-generation infection outside the original city (Wuhan): An observational study
title_fullStr Changes in CT manifestations and RT-PCR testings of the coronavirus disease 2019 until recovery in patients with afferent infection vs. second-generation infection outside the original city (Wuhan): An observational study
title_full_unstemmed Changes in CT manifestations and RT-PCR testings of the coronavirus disease 2019 until recovery in patients with afferent infection vs. second-generation infection outside the original city (Wuhan): An observational study
title_short Changes in CT manifestations and RT-PCR testings of the coronavirus disease 2019 until recovery in patients with afferent infection vs. second-generation infection outside the original city (Wuhan): An observational study
title_sort changes in ct manifestations and rt-pcr testings of the coronavirus disease 2019 until recovery in patients with afferent infection vs. second-generation infection outside the original city (wuhan): an observational study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414381/
https://www.ncbi.nlm.nih.gov/pubmed/32838010
http://dx.doi.org/10.1016/j.jrid.2020.07.007
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