Human cytomegalovirus major immediate early transcripts arise predominantly from the canonical major immediate early promoter in reactivating progenitor-derived dendritic cells

Human cytomegalovirus latency and reactivation is a major source of morbidity in immune-suppressed patient populations. Lifelong latent infections are established in CD34+progenitor cells in the bone marrow, which are hallmarked by a lack of major lytic gene expression, genome replication and virus...

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Detalles Bibliográficos
Autores principales: Mason, Rebecca, Groves, Ian J., Wills, Mark R., Sinclair, John H., Reeves, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414444/
https://www.ncbi.nlm.nih.gov/pubmed/32375946
http://dx.doi.org/10.1099/jgv.0.001419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414444/
https://www.ncbi.nlm.nih.gov/pubmed/32375946
http://dx.doi.org/10.1099/jgv.0.001419

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