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Therapeutic role of recurrent ESR1-CCDC170 gene fusions in breast cancer endocrine resistance
BACKGROUND: Endocrine therapy is the most common treatment for estrogen receptor (ER)-positive breast cancer, but its effectiveness is limited by high rates of primary and acquired resistance. There are likely many genetic causes, and recent studies suggest the important role of ESR1 mutations and f...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414578/ https://www.ncbi.nlm.nih.gov/pubmed/32771039 http://dx.doi.org/10.1186/s13058-020-01325-3 |