Cargando…

Use of convalescent plasma in hospitalized patients with COVID-19: case series

Two case series examining the impact of convalescent plasma on patients with COVID-19 suggest some clinical benefit from early administration and modest impact on parameters of inflammation. Further assessment of the impact of this intervention awaits controlled clinical trials.

Detalles Bibliográficos
Autores principales: Hegerova, Livia, Gooley, Ted A., Sweerus, Kelly A., Maree, Cynthia, Bailey, Neil, Bailey, Megumi, Dunleavy, Vanessa, Patel, Krish, Alcorn, Kirsten, Haley, Rebecca, Johnsen, Jill M., Konkle, Barbara A., Lahti, Annamarie C., Alexander, Morgan L., Goldman, Jason D., Lipke, Anne, Lim, Sun-jung, Sullivan, Mark D., Pauk, John S., Pagel, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414587/
https://www.ncbi.nlm.nih.gov/pubmed/32559767
http://dx.doi.org/10.1182/blood.2020006964
_version_ 1783568998031425536
author Hegerova, Livia
Gooley, Ted A.
Sweerus, Kelly A.
Maree, Cynthia
Bailey, Neil
Bailey, Megumi
Dunleavy, Vanessa
Patel, Krish
Alcorn, Kirsten
Haley, Rebecca
Johnsen, Jill M.
Konkle, Barbara A.
Lahti, Annamarie C.
Alexander, Morgan L.
Goldman, Jason D.
Lipke, Anne
Lim, Sun-jung
Sullivan, Mark D.
Pauk, John S.
Pagel, John M.
author_facet Hegerova, Livia
Gooley, Ted A.
Sweerus, Kelly A.
Maree, Cynthia
Bailey, Neil
Bailey, Megumi
Dunleavy, Vanessa
Patel, Krish
Alcorn, Kirsten
Haley, Rebecca
Johnsen, Jill M.
Konkle, Barbara A.
Lahti, Annamarie C.
Alexander, Morgan L.
Goldman, Jason D.
Lipke, Anne
Lim, Sun-jung
Sullivan, Mark D.
Pauk, John S.
Pagel, John M.
author_sort Hegerova, Livia
collection PubMed
description Two case series examining the impact of convalescent plasma on patients with COVID-19 suggest some clinical benefit from early administration and modest impact on parameters of inflammation. Further assessment of the impact of this intervention awaits controlled clinical trials.
format Online
Article
Text
id pubmed-7414587
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher American Society of Hematology
record_format MEDLINE/PubMed
spelling pubmed-74145872020-09-09 Use of convalescent plasma in hospitalized patients with COVID-19: case series Hegerova, Livia Gooley, Ted A. Sweerus, Kelly A. Maree, Cynthia Bailey, Neil Bailey, Megumi Dunleavy, Vanessa Patel, Krish Alcorn, Kirsten Haley, Rebecca Johnsen, Jill M. Konkle, Barbara A. Lahti, Annamarie C. Alexander, Morgan L. Goldman, Jason D. Lipke, Anne Lim, Sun-jung Sullivan, Mark D. Pauk, John S. Pagel, John M. Blood Letter to Blood Two case series examining the impact of convalescent plasma on patients with COVID-19 suggest some clinical benefit from early administration and modest impact on parameters of inflammation. Further assessment of the impact of this intervention awaits controlled clinical trials. American Society of Hematology 2020-08-06 2020-12-14 /pmc/articles/PMC7414587/ /pubmed/32559767 http://dx.doi.org/10.1182/blood.2020006964 Text en Copyright © 2020 American Society of Hematology. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Letter to Blood
Hegerova, Livia
Gooley, Ted A.
Sweerus, Kelly A.
Maree, Cynthia
Bailey, Neil
Bailey, Megumi
Dunleavy, Vanessa
Patel, Krish
Alcorn, Kirsten
Haley, Rebecca
Johnsen, Jill M.
Konkle, Barbara A.
Lahti, Annamarie C.
Alexander, Morgan L.
Goldman, Jason D.
Lipke, Anne
Lim, Sun-jung
Sullivan, Mark D.
Pauk, John S.
Pagel, John M.
Use of convalescent plasma in hospitalized patients with COVID-19: case series
title Use of convalescent plasma in hospitalized patients with COVID-19: case series
title_full Use of convalescent plasma in hospitalized patients with COVID-19: case series
title_fullStr Use of convalescent plasma in hospitalized patients with COVID-19: case series
title_full_unstemmed Use of convalescent plasma in hospitalized patients with COVID-19: case series
title_short Use of convalescent plasma in hospitalized patients with COVID-19: case series
title_sort use of convalescent plasma in hospitalized patients with covid-19: case series
topic Letter to Blood
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414587/
https://www.ncbi.nlm.nih.gov/pubmed/32559767
http://dx.doi.org/10.1182/blood.2020006964
work_keys_str_mv AT hegerovalivia useofconvalescentplasmainhospitalizedpatientswithcovid19caseseries
AT gooleyteda useofconvalescentplasmainhospitalizedpatientswithcovid19caseseries
AT sweeruskellya useofconvalescentplasmainhospitalizedpatientswithcovid19caseseries
AT mareecynthia useofconvalescentplasmainhospitalizedpatientswithcovid19caseseries
AT baileyneil useofconvalescentplasmainhospitalizedpatientswithcovid19caseseries
AT baileymegumi useofconvalescentplasmainhospitalizedpatientswithcovid19caseseries
AT dunleavyvanessa useofconvalescentplasmainhospitalizedpatientswithcovid19caseseries
AT patelkrish useofconvalescentplasmainhospitalizedpatientswithcovid19caseseries
AT alcornkirsten useofconvalescentplasmainhospitalizedpatientswithcovid19caseseries
AT haleyrebecca useofconvalescentplasmainhospitalizedpatientswithcovid19caseseries
AT johnsenjillm useofconvalescentplasmainhospitalizedpatientswithcovid19caseseries
AT konklebarbaraa useofconvalescentplasmainhospitalizedpatientswithcovid19caseseries
AT lahtiannamariec useofconvalescentplasmainhospitalizedpatientswithcovid19caseseries
AT alexandermorganl useofconvalescentplasmainhospitalizedpatientswithcovid19caseseries
AT goldmanjasond useofconvalescentplasmainhospitalizedpatientswithcovid19caseseries
AT lipkeanne useofconvalescentplasmainhospitalizedpatientswithcovid19caseseries
AT limsunjung useofconvalescentplasmainhospitalizedpatientswithcovid19caseseries
AT sullivanmarkd useofconvalescentplasmainhospitalizedpatientswithcovid19caseseries
AT paukjohns useofconvalescentplasmainhospitalizedpatientswithcovid19caseseries
AT pageljohnm useofconvalescentplasmainhospitalizedpatientswithcovid19caseseries