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Improved clinical symptoms and mortality among patients with severe or critical COVID-19 after convalescent plasma transfusion

Two case series examining the impact of convalescent plasma on patients with COVID-19 suggest some clinical benefit from early administration and modest impact on parameters of inflammation. Further assessment of the impact of this intervention awaits controlled clinical trials.

Detalles Bibliográficos
Autores principales: Xia, Xinyi, Li, Kening, Wu, Lingxiang, Wang, Zhihua, Zhu, Mengyan, Huang, Bin, Li, Jie, Wang, Ziyu, Wu, Wei, Wu, Min, Li, Wanlin, Li, Lu, Cai, Yun, Bosco, Bakwatanisa, Zhong, Aifang, Liu, Xiong, Lv, Tangfeng, Gan, Zhenhua, Chen, Guang, Pan, Yunhu, Liu, Caidong, Zhang, Kai, Xu, Xiaoli, Wang, Changjun, Wang, Qianghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414593/
https://www.ncbi.nlm.nih.gov/pubmed/32573724
http://dx.doi.org/10.1182/blood.2020007079
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author Xia, Xinyi
Li, Kening
Wu, Lingxiang
Wang, Zhihua
Zhu, Mengyan
Huang, Bin
Li, Jie
Wang, Ziyu
Wu, Wei
Wu, Min
Li, Wanlin
Li, Lu
Cai, Yun
Bosco, Bakwatanisa
Zhong, Aifang
Liu, Xiong
Lv, Tangfeng
Gan, Zhenhua
Chen, Guang
Pan, Yunhu
Liu, Caidong
Zhang, Kai
Xu, Xiaoli
Wang, Changjun
Wang, Qianghu
author_facet Xia, Xinyi
Li, Kening
Wu, Lingxiang
Wang, Zhihua
Zhu, Mengyan
Huang, Bin
Li, Jie
Wang, Ziyu
Wu, Wei
Wu, Min
Li, Wanlin
Li, Lu
Cai, Yun
Bosco, Bakwatanisa
Zhong, Aifang
Liu, Xiong
Lv, Tangfeng
Gan, Zhenhua
Chen, Guang
Pan, Yunhu
Liu, Caidong
Zhang, Kai
Xu, Xiaoli
Wang, Changjun
Wang, Qianghu
author_sort Xia, Xinyi
collection PubMed
description Two case series examining the impact of convalescent plasma on patients with COVID-19 suggest some clinical benefit from early administration and modest impact on parameters of inflammation. Further assessment of the impact of this intervention awaits controlled clinical trials.
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spelling pubmed-74145932020-09-09 Improved clinical symptoms and mortality among patients with severe or critical COVID-19 after convalescent plasma transfusion Xia, Xinyi Li, Kening Wu, Lingxiang Wang, Zhihua Zhu, Mengyan Huang, Bin Li, Jie Wang, Ziyu Wu, Wei Wu, Min Li, Wanlin Li, Lu Cai, Yun Bosco, Bakwatanisa Zhong, Aifang Liu, Xiong Lv, Tangfeng Gan, Zhenhua Chen, Guang Pan, Yunhu Liu, Caidong Zhang, Kai Xu, Xiaoli Wang, Changjun Wang, Qianghu Blood Letter to Blood Two case series examining the impact of convalescent plasma on patients with COVID-19 suggest some clinical benefit from early administration and modest impact on parameters of inflammation. Further assessment of the impact of this intervention awaits controlled clinical trials. American Society of Hematology 2020-08-06 2020-12-14 /pmc/articles/PMC7414593/ /pubmed/32573724 http://dx.doi.org/10.1182/blood.2020007079 Text en Copyright © 2020 American Society of Hematology. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Letter to Blood
Xia, Xinyi
Li, Kening
Wu, Lingxiang
Wang, Zhihua
Zhu, Mengyan
Huang, Bin
Li, Jie
Wang, Ziyu
Wu, Wei
Wu, Min
Li, Wanlin
Li, Lu
Cai, Yun
Bosco, Bakwatanisa
Zhong, Aifang
Liu, Xiong
Lv, Tangfeng
Gan, Zhenhua
Chen, Guang
Pan, Yunhu
Liu, Caidong
Zhang, Kai
Xu, Xiaoli
Wang, Changjun
Wang, Qianghu
Improved clinical symptoms and mortality among patients with severe or critical COVID-19 after convalescent plasma transfusion
title Improved clinical symptoms and mortality among patients with severe or critical COVID-19 after convalescent plasma transfusion
title_full Improved clinical symptoms and mortality among patients with severe or critical COVID-19 after convalescent plasma transfusion
title_fullStr Improved clinical symptoms and mortality among patients with severe or critical COVID-19 after convalescent plasma transfusion
title_full_unstemmed Improved clinical symptoms and mortality among patients with severe or critical COVID-19 after convalescent plasma transfusion
title_short Improved clinical symptoms and mortality among patients with severe or critical COVID-19 after convalescent plasma transfusion
title_sort improved clinical symptoms and mortality among patients with severe or critical covid-19 after convalescent plasma transfusion
topic Letter to Blood
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414593/
https://www.ncbi.nlm.nih.gov/pubmed/32573724
http://dx.doi.org/10.1182/blood.2020007079
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