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A novel path-specific effect statistic for identifying the differential specific paths in systems epidemiology

BACKGROUND: Biological pathways play an important role in the occurrence, development and recovery of complex diseases, such as cancers, which are multifactorial complex diseases that are generally caused by mutation of multiple genes or dysregulation of pathways. RESULTS: We propose a path-specific...

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Detalles Bibliográficos
Autores principales: Li, Hongkai, Geng, Zhi, Sun, Xiaoru, Yu, Yuanyuan, Xue, Fuzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414699/
https://www.ncbi.nlm.nih.gov/pubmed/32770935
http://dx.doi.org/10.1186/s12863-020-00876-w