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A novel path-specific effect statistic for identifying the differential specific paths in systems epidemiology
BACKGROUND: Biological pathways play an important role in the occurrence, development and recovery of complex diseases, such as cancers, which are multifactorial complex diseases that are generally caused by mutation of multiple genes or dysregulation of pathways. RESULTS: We propose a path-specific...
Autores principales: | Li, Hongkai, Geng, Zhi, Sun, Xiaoru, Yu, Yuanyuan, Xue, Fuzhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414699/ https://www.ncbi.nlm.nih.gov/pubmed/32770935 http://dx.doi.org/10.1186/s12863-020-00876-w |
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