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The oncogenic potential of a mutant TP53 gene explored in two spontaneous lung cancer mice models
BACKGROUND: Lung cancer is the number one cancer killer worldwide. A major drawback in the lung cancer treatment field is the lack of realistic mouse models that replicate the complexity of human malignancy and immune contexture within the tumor microenvironment. Such models are urgently needed. Mut...
Autores principales: | Ramelow, Julian, Brooks, Christopher D., Gao, Li, Almiman, Abeer A., Williams, Terence M., Villalona-Calero, Miguel A., Duan, Wenrui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414707/ https://www.ncbi.nlm.nih.gov/pubmed/32770960 http://dx.doi.org/10.1186/s12885-020-07212-6 |
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