Loss of survival advantage for deficient mismatch repair in patients with advanced colorectal cancer may be caused by changes in prognostic value of CD8+T cell

BACKGROUND: Patients with stage II deficient mismatch repair (dMMR) show a better prognosis than patients with colorectal cancer (CRC) with proficient mismatch repair (pMMR). However, this beneficial effect is decreased in advanced stages of the disease. This study was conducted to investigate the p...

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Detalles Bibliográficos
Autores principales: Wang, Bingyan, Li, Fei, Guo, Limei, Lu, Siyi, Ma, Junren, Ma, Yanpeng, Meng, Yan, Wang, Junwei, Zhou, Xin, Fu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414758/
https://www.ncbi.nlm.nih.gov/pubmed/32767974
http://dx.doi.org/10.1186/s12957-020-01970-0

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