Cargando…
Novel multiparameter correlates of Coxiella burnetii infection and vaccination identified by longitudinal deep immune profiling
Q-fever is a flu-like illness caused by Coxiella burnetii (Cb), a highly infectious intracellular bacterium. There is an unmet need for a safe and effective vaccine for Q-fever. Correlates of immune protection to Cb infection are limited. We proposed that analysis by longitudinal high dimensional im...
Autores principales: | Reeves, P. M., Raju Paul, S., Baeten, L., Korek, S. E., Yi, Y., Hess, J., Sobell, D., Scholzen, A., Garritsen, A., De Groot, A. S., Moise, L., Brauns, T., Bowen, R., Sluder, A. E., Poznansky, M. C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414860/ https://www.ncbi.nlm.nih.gov/pubmed/32770104 http://dx.doi.org/10.1038/s41598-020-69327-x |
Ejemplares similares
-
Promiscuous Coxiella burnetii CD4 Epitope Clusters Associated With Human Recall Responses Are Candidates for a Novel T-Cell Targeted Multi-Epitope Q Fever Vaccine
por: Scholzen, Anja, et al.
Publicado: (2019) -
Cytometry profiling of ex vivo recall responses to Coxiella burnetii in previously naturally exposed individuals reveals long-term changes in both adaptive and innate immune cellular compartments
por: Raju Paul, Susan, et al.
Publicado: (2023) -
Evaluation of a Human T Cell-Targeted Multi-Epitope Vaccine for Q Fever in Animal Models of Coxiella burnetii Immunity
por: Sluder, Ann E., et al.
Publicado: (2022) -
Q-vaxcelerate: A distributed development approach for a new Coxiella burnetii vaccine
por: Reeves, Patrick M., et al.
Publicado: (2017) -
Natural Exposure- and Vaccination-Induced Profiles of Ex Vivo Whole Blood Cytokine Responses to Coxiella burnetii
por: Raju Paul, Susan, et al.
Publicado: (2022)