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Spray dried VSV-vectored vaccine is thermally stable and immunologically active in vivo
Effective vaccine delivery and coverage to rural and resource-poor countries is hindered by the dependence on cold chain storage. As such, developments of cold chain-free technologies are highly sought. Although spray dried adenoviral vectors have shown long term stability at ambient temperatures an...
Autores principales: | Toniolo, Steven P., Afkhami, Sam, D’Agostino, Michael R., Lichty, Brian D., Cranston, Emily D., Xing, Zhou, Thompson, Michael R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414861/ https://www.ncbi.nlm.nih.gov/pubmed/32770018 http://dx.doi.org/10.1038/s41598-020-70325-2 |
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