A chimeric mouse model to study human iPSC-derived neurons: the case of a truncating SHANK3 mutation

Using human induced pluripotent stem cells (iPSC), recent studies have shown that the events underlying autism spectrum disorders (ASD) can occur during neonatal development. We previously analyzed the iPSC-derived pyramidal cortical neurons of a subset of patients with ASD carrying de novo heterozy...

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Detalles Bibliográficos
Autores principales: Vitrac, Aline, Pons, Stéphanie, Balkota, Marta, Lemière, Nathalie, Raïs, Célia, Bourgeois, Jean-Pierre, Maskos, Uwe, Bourgeron, Thomas, Cloëz-Tayarani, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414912/
https://www.ncbi.nlm.nih.gov/pubmed/32769989
http://dx.doi.org/10.1038/s41598-020-70056-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414912/
https://www.ncbi.nlm.nih.gov/pubmed/32769989
http://dx.doi.org/10.1038/s41598-020-70056-4

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