Microglia depletion diminishes key elements of the leukotriene pathway in the brain of Alzheimer’s Disease mice

Leukotrienes (LTs) contribute to the neuropathology of chronic neurodegenerative disorders including Alzheimer’s Disease (AD), where they mediate neuroinflammation and neuronal cell-death. In consequence, blocking the action of Leukotrienes (LTs) ameliorates pathologies and improves cognitive functi...

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Detalles Bibliográficos
Autores principales: Michael, J., Unger, M. S., Poupardin, R., Schernthaner, P., Mrowetz, H., Attems, J., Aigner, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414992/
https://www.ncbi.nlm.nih.gov/pubmed/32771067
http://dx.doi.org/10.1186/s40478-020-00989-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414992/
https://www.ncbi.nlm.nih.gov/pubmed/32771067
http://dx.doi.org/10.1186/s40478-020-00989-4

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