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Microglia depletion diminishes key elements of the leukotriene pathway in the brain of Alzheimer’s Disease mice
Leukotrienes (LTs) contribute to the neuropathology of chronic neurodegenerative disorders including Alzheimer’s Disease (AD), where they mediate neuroinflammation and neuronal cell-death. In consequence, blocking the action of Leukotrienes (LTs) ameliorates pathologies and improves cognitive functi...
Autores principales: | Michael, J., Unger, M. S., Poupardin, R., Schernthaner, P., Mrowetz, H., Attems, J., Aigner, L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414992/ https://www.ncbi.nlm.nih.gov/pubmed/32771067 http://dx.doi.org/10.1186/s40478-020-00989-4 |
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